UORSY New Generation Screening Library contains about 1,900,000 compounds. The library is a revolutionary collection of lead-like molecules with outstanding structural quality and diversity—New Generation Screening Library (NGSL). Its core is decorated with interesting building blocks, including important medicinal fragments such as peptide bonds, amino groups and hydroxyl groups. and designed for discovery of new Voltage-gated calcium channel blockers.
ASINEX has elaborated a library of diverse macrocycles using an effective tool box of synthetic methods. The resulting scaffolds are novel, tremendously diverse, medchem-relevant, macrocyclic frameworks.
Macrocyles tend to be larger than traditional screening molecules which make them perfect discovery tools for targets with shallow or extended binding sites. At the same time, their unique character based on restricted flexibility and ability to form intra-molecular hydrogen bonds allows for design approaches effectively optimizing properties such asaqueous solubility and membrane permeability. Many of these macrocycles have been tested for aqueous and DMSO solubility with cut-offs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4) followed by PAMPA permeability assay.
肽去甲酰基酶是蛋白质生物合成中的关键酶,可催化去除新合成蛋白质 N 末端甲硫氨酸的甲酰基。该酶在 N 端 L-甲硫氨酸以外的位置显示出广泛的特异性,可确保蛋白质的适当成熟和功能,强调其对蛋白质合成和修饰的复杂过程的重要贡献。Peptide deformylase Protein, S. aureus (P.pastoris, His) 是重组的 肽去甲酰化酶蛋白,由 P. pastoris 表达,带有 N-6*His 标签。
Progonadoliberin-2/GNRH II 蛋白是内分泌系统中的关键角色,可有效刺激促性腺激素分泌,促进黄体生成素 (LH) 和卵泡刺激素 (FSH) 的释放。它协调这些激素分泌的能力强调了它在调节生殖轴的复杂内分泌信号网络中控制生殖功能的重要性。Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) 是重组的 Progonadoliberin-2/GNRH II 蛋白,由 HEK293 表达,带有 C-6*His 标签。
PNGase F 蛋白充当酶催化剂,专门从糖蛋白中裂解整个聚糖。该过程取决于糖基化天冬酰胺部分在其氨基 (R1) 和羧基 (R2) 末端均被多肽链取代,如反应 1 所示。PNGase F Protein, F. meningosepticum (His) 是重组的 PNGase F 蛋白,由 E. coli 表达,带有 N-His 标签。PNGase F Protein, F. meningosepticum (His) 全长 314 个氨基酸,分子量约为 ~35 kDa。
Growth factor-like Peptide; Leader protein; Non-structural protein 10; Non-structural protein 2; Non-structural protein 3; Non-structural protein 4; Non-structural protein 6; Non-structural protein 7; Non-structural protein 8; Non-structural protein 9; Papain-like proteinase; p65 homolog
Natriuretic Peptides A Antibody (YA1381) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1381), targeting Natriuretic Peptides A, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). Natriuretic Peptides A Antibody (YA1381) can be used for WB, IP experiment in human background.
GLP-1R Antibody is an unconjugated, approximately 51 kDa, rabbit-derived, anti-GLP-1R polyclonal antibody. GLP-1R Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: dog background without labeling.
Klotho Antibody (YA3355) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3355), targeting Klotho, with a predicted molecular weight of 116 kDa (observed band size: 62 kDa). Klotho Antibody (YA3355) can be used for WB, IHC-P experiment in human, mouse background.
Obestatin Antibody (YA1227) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1227), targeting Obestatin. Obestatin Antibody (YA1227) can be used for IHC-P experiment in human background.
Natriuretic Peptides B Antibody (YA999) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA999), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA999) can be used for ELISA experiment in human background.
Natriuretic Peptides B Antibody (YA1000) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1000), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA1000) can be used for ELISA experiment in human background.
Natriuretic Peptides B Antibody (YA1001) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1001), targeting Natriuretic Peptides B. Natriuretic Peptides B Antibody (YA1001) can be used for ELISA experiment in human background.
Chromogranin B Antibody (YA2422) is a biotin-conjugated non-conjugated IgG antibody, targeting Chromogranin B, with a predicted molecular weight of 78 kDa (observed band size: 125 kDa). Chromogranin B Antibody (YA2422) can be used for WB experiment in human, mouse, rat background.
AMCFII; C-X-C motif chemokine 5; Cxcl5; CXCL5_HUMAN; ENA-78(1-78); ENA-78(9-78); ENA78; Epithelial derived neutrophil activating Peptide 78; Epithelial derived neutrophil activating protein 78; Epithelial-derived neutrophil-activating protein 78; GCP2; LIX; Neutrophil activating Peptide ENA 78; Neutrophil-activating Peptide ENA-78; SCYB5; Scyb6; Small inducible cytokine B5; Small inducible cytokine subfamily B member 5; Small-inducible cytokine B5.
WB, ICC/IF, IP
Human
CXCL5 Antibody is an unconjugated, approximately 10 kDa, rabbit-derived, anti-CXCL5 monoclonal antibody. CXCL5 Antibody can be used for: WB,ICC/IF,IP expriments in human background without labeling.
Haptoglobin Antibody (YA2545) is a biotin-conjugated non-conjugated IgG antibody, targeting Haptoglobin, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). Haptoglobin Antibody (YA2545) can be used for WB experiment in human, mouse, rat background.
POMC Antibody (YA1619) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1619), targeting POMC, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). POMC Antibody (YA1619) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.
INSL3 Antibody (YA1241) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1241), targeting INSL3. INSL3 Antibody (YA1241) can be used for IHC-P experiment in human background.
Calcitonin Antibody is an unconjugated, rabbit-derived, anti-Calcitonin monoclonal antibody. Calcitonin Antibody can be used for: IHC-P expriments in human background without labeling.
Amyloid Precursor Protein Antibody (YA1130) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1130), targeting Amyloid Precursor Protein. Amyloid Precursor Protein Antibody (YA1130) can be used for IHC-P experiment in human background.
Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2568), targeting Phospho-Amyloid Precursor Protein (Thr743), with a predicted molecular weight of 87 kDa (observed band size: 100 kDa). Phospho-Amyloid Precursor Protein (Thr743) Antibody (YA2568) can be used for WB, ICC/IF, IP experiment in human, rat background.
PTH1R; PTHR; PTHR1; Parathyroid hormone/parathyroid hormone-related Peptide receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor; PTH1 receptor
WB, IP
Human
Parathyroid Hormone Receptor 1 Antibody (YA1452) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1452), targeting Parathyroid Hormone Receptor 1, with a predicted molecular weight of 66 kDa (observed band size: 66 kDa). Parathyroid Hormone Receptor 1 Antibody (YA1452) can be used for WB, IP experiment in human background.
VIPR1 Antibody (YA1269) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1269), targeting VIPR1. VIPR1 Antibody (YA1269) can be used for IHC-P experiment in human background.
GRP75 Antibody (YA3155) is a biotin-conjugated non-conjugated IgG antibody, targeting GRP75, with a predicted molecular weight of 74 kDa. GRP75 Antibody (YA3155) can be used for WB experiment in human, mouse, rat background.
JMJD6; KIAA0585; PTDSR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-diox
WB, ICC/IF
Human
JMJD6 Antibody (YA1064) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA1064), targeting JMJD6, with a predicted molecular weight of 46 kDa (observed band size: 62 kDa). JMJD6 Antibody (YA1064) can be used for WB, ICC/IF experiment in human background.
CCR7_HUMAN; BLR 2; BLR2; C C chemokine receptor type 7; C C CKR 7; CC chemokine receptor 7; CC chemokine receptor type 7; CC CKR 7; CCCKR7; CCR 7; CD 197; CD197; CD197 antigen; CDW197; Chemokine C C motif receptor 7; Chemokine C C receptor 7; Chemokine receptor 7-like protein; EBI 1; EBI1; Ebi1h; EBV Induced G Protein Coupled Receptor 1; Epstein Barr virus induced G protein coupled receptor; Epstein Barr virus induced gene 1; EVI 1; EVI1; Lymphocyte Specific G Protein Coupled Peptide Receptor; MGC108519; MIP 3 beta receptor; MIP3 Beta Receptor.
WB, IHC-P, ICC/IF, ELISA
Human, Mouse, Rat
CCR7 Antibody is an unconjugated, approximately 42 kDa, rabbit-derived, anti-CCR7 polyclonal antibody. CCR7 Antibody can be used for: WB, ELISA, IHC-P, ICC, IF expriments in human, mouse, rat, and predicted: dog background without labeling.
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